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. 2020 Jan 12;7(2):ofaa014. doi: 10.1093/ofid/ofaa014

Table 1.

Patients Receiving CI C/T Outpatient Therapy

Patient Infectious Diagnosis Pathogen Susceptible to C/T? Antibiotic Allergies Dose/Day (Grams) Duration (Days) Satisfaction Score (avg)
1a,b cUTI MDR Pseudomonas aeruginosa Susceptible (25-mm zone diameter) PCN 4.5 14 N/A
2a Pneumonia P aeruginosa Not tested None 4.5 17 N/A
3a Pneumonia P aeruginosa Not tested None 9 6 N/A
4 Discitis P aeruginosa Not tested PCN 4.5 42 N/A
5a,b cUTI MDR P aeruginosa Intermediate (Etest MIC = 8/4 mcg/mL) Erythromycin 4.5 7 4
6a,b Bacteremia P aeruginosa Escherichia coli Not tested PCN, Sulfa 4.5 10 4.2
7a Pneumonia MDR P aeruginosa Susceptible (Etest MIC 2/4 mcg/mL) Doxycycline 4.5 14 5

Abbreviations: avg, average; CI, continuous infusion; C/T, ceftolozane/tazobactam; cUTI, complicated urinary tract infection; MDR, multidrug-resistant; MIC, minimum inhibitory concentration; N/A, not applicable; PCN, penicillin.

aClinical cure (6 of 7 patients).

bMicrobiological cure (3 of 3 patients).