Table 3.
Overall test characteristics
| Test variable | Anti-PLA2R ChLIAa | Anti-PLA2R ELISAa | Anti-PLA2R RC-IFAa |
|---|---|---|---|
| Area under the curve (95% CI) | 0.899 (0.854–0.944) | 0.927 (0.894–0.961) | 0.916 (0.880–0.952) |
| Maximum sum of sensitivity and specificity, % (cutoff) | 183.9 (9.1) | 181.3 (3.0) | 183.2 (1:5) |
| Sensitivity at 98% specificity, % (cutoff) | 85.2 (7.8) | 81.9 (5.8) | NA |
| Sensitivity at 99% specificity, % (cutoff) | 84.5 (9.1) | 80.7 (7.3) | NA |
| Sensitivity at 100% specificity, % (cutoff) | 83.2 (15.5) | 76.1 (15.2) | 83.2 (1:5) |
Anti-PLRA2, anti–phospholipase A2 receptor; ChLIA, chemiluminescence immunoassay; CI, confidence interval; ELISA, enzyme-linked immunosorbent assay; NA, not available; RC-IFA, recombinant cell-based indirect immunofluorescence assay; RU, relative units.
a
Cutoff values are indicated in chemiluminescent units per milliliter (ChLIA), RU/ml (ELISA), and titer (RC-IFA).