Table 3. Number of post-operative complications, n. and doses of post-operative administration of labetalol, dexmedetomidine and acepromazine.
| Information recorded | Sevo-Op | Sevo-Dex | p value | Sevo-Op vs. Sevo-Dex | |
|---|---|---|---|---|---|
| OR (95% CI) | p value | ||||
| Postoperative complications (No.) | 4 Bradycardia | 10 Bradycardia | 0.35 | 3.33 (0.50–22.14) | 0.21 |
| 1 Tachycardia | 2 Tachycardia | 0.99 | 1.27 (0.096–16.81) | 0.85 | |
| 3 Hypertension | 8 Hypertension | 0.39 | 2.67 (0.43–16.40) | 0.29 | |
| 4 Agitation | 8 Agitation | 0.67 | 1.6 (0.27–9.49) | 0.60 | |
| 0 Seizures | 1 Seizures | 0.99 | 2.0 (0.074–56.27) | 0.67 | |
| 2 Hypothermia | 8 Hypothermia | 0.18 | 4.8 (0.68–33.8) | 0.12 | |
| 0 Hyperthermia | 2 Hyperthermia | 0.50 | 3.7 (0.16–87.39) | 0.42 | |
| Postoperative labetalol administration (No.) [(dose in mg/kg/h)] | 2 [1.75 (1.5–2)] | 6 [1.9 (1.3–2.4)] | 0.40 | 2.57 (0.37–17.83) | 0.34 |
| Postoperative dexmedetomidine administration (No.) [(dose in µg/kg/min)] | 7 [0.015 (0.008–0.025)] | 13 [0.011 (0.005–0.023)] | 0.38 | 5.4 (0.19–149.79) | 0.32 |
| Reason for postoperative dexmedetomidine (No.) | 6 Preemptive | 13 Preemptive | 0.35 | - | - |
| 1 Reactive | 0 Reactive | ||||
| Postoperative acepromazine administration (No.) [(dose in µg/kg)] | 5 [8.8 (5–10)] | 9 [10.4 (7–20)] | 0.99 | 1.35 (0.21–8.62) | 0.75 |
OR and 95% CI are reported. The p values, unless otherwise stated, correspond to statistical test comparing number of animals receiving treatment rather than the dose.
OR, odds ration; CI, confidence interval; Group Sevo-Op, sevoflurane and short acting opioid infusion; Group Sevo-Dex, sevoflurane and dexmedetomidine infusion.