Table 3. . Cox proportional hazards model for overall survival.

Characteristics	HR (95% CI)	p-value
Histopathology – Poorly differentiated† – Moderately differentiated – Well differentiated	1.0 (0.2–4.0) 4.0 (0.4–38.5)	0.943 0.230
LGR5 status – High† – Low	3.3 (1.1–9.7)	0.029
Distant metastasis – Distant metastasis† – vs no distant metastasis	0.7 (0.1–3.5)	0.678
Gender – Female† – vs male	2.1 (0.6–7.1)	0.226
Age at diagnosis	1.0 (0.9–1.0)	0.995
Lymph node status – Negative† – vs positive	1.3 (0.1–12.6)	0.777
American Joint Committee on Cancer staging – Stage 1† – Stage 2 – Stage 3 – Stage 4	0.8 (0.1–7.2) 1.9 (0.0–39.4) 0.9 (0.0–15.2)	0.901 0.678 0.949

^†Reference group.

HR: Hazard ratio.