TABLE 2.
Variants in the coding sequence of the Ifnar1 gene
Positiona | dbSNPb annotation | Nucleotide in the Ifnar1 gene of the CC founder strains: |
Amino acid position | Amino acid changec | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Reference (B6) | 129S1/SvImJ | A/J | CAST/EiJ | NOD/ShiLtJ | NZO/HILtJ | PWK/PhJ | WSB/EiJ | ||||
91,485,366 | rs235809125 | C | —d | — | T | — | — | — | — | 8 | A → V |
91,485,368 | rs255866699 | G | — | — | A | — | — | — | — | 9 | A → T |
91,499,433 | rs31418313 | G | — | A | — | — | — | — | — | 274 | R → H |
91,499,468 | rs223171563 | A | — | — | G | — | — | — | — | 286 | N → D |
91,499,532 | rs240163845 | A | — | — | G | — | — | G | — | 307 | H → R |
91,501,623 | rs263194450 | T | — | — | G | — | — | G | — | 376 | I → R |
91,501,631 | rs246470801 | G | — | — | A | — | — | A | — | 379 | E → K |
91,505,284 | rs219805193 | C | — | — | T | — | — | — | — | 549 | A → V |
The sequences at positions 91,485,344 to 91,505,411 on chromosome 16 were retrieved from the Sanger Institute Mouse Genomes Project (https://www.sanger.ac.uk/sanger/Mouse_SnpViewer/rel-1505).
dbSNP, Single Nucleotide Polymorphism Database.
Amino acid changes compared with the reference (B6 mouse) sequence (CCDS database; https://www.ncbi.nlm.nih.gov/CCDS/).
—, no nucleotide change.