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. 2019 Sep 13;28(2):653–663. doi: 10.1016/j.ymthe.2019.09.013

Figure 3.

Figure 3

miR-223 Deletion Worsens EAH

(A) Schematic representation of EAH induction in WT or miR-223-deficient (miR-223−/−) mice with LPS/D-GalN. (B) Staining of total macrophages (F4/80), monocytes (Ly6C), and neutrophils (MPO) with anti-F4/80, Ly6C, or MPO antibodies in liver slides. Scale bars, 100 μm. (C) Levels of ALT in serum. (D–F) Percentage of liver area stained positive for anti-F4/80 (D), MPO (E), or Ly6C (F) antibodies. ***p < 0.001, ****p < 0.0001, one-way ANOVA. Data show means ± SD, n = 5–7/group.