Table 4.
| |||||
Genotypes | Gender | PACG patients N (%) | Controls N (%) | OR (95%CI) | P-value |
rs736893 | 0.001 | ||||
G/G | Male | 5(9) | 19(37) | Reference | Reference |
G/A | 48(91) | 32(63) | 5(1.5–16.5) | 0.007 | |
A/A | 0(0) | 0(0) | – | – | |
G/G | Female | 5(7) | 27(34) | Reference | Reference |
G/A | 72(93) | 52(66) | 7(2.5–22.2) | 0.01 | |
A/A | 0(0) | 0(0) | – | – | |
rs1258267 | 0.02 | ||||
A/A | Male | 39(74) | 43(84) | Reference | Reference |
A/G | 12(22) | 8(16) | 2.7(0.8–9.2) | 0.1 | |
G/G | 2(4) | 0(0) | 10(0.1–11.1) | 0.98 | |
A/A | Female | 58(75) | 70(89) | Reference | Reference |
A/G | 18(23) | 9(11) | 1.5(0.6–4) | 0.3 | |
G/G | 1(2) | 0(0) | 11(0.6–27.4) | 0.8 | |
rs3816415 | 0.005 | ||||
C/C | Male | 47(89) | 51(11) | Reference | Reference |
C/T | 6(11) | 0(0) | 18(0.2–23.4) | 0.98 | |
T/T | 0(0) | 0(0) | – | – | |
C/C | Female | 73(95) | 78(99) | Reference | Reference |
C/T | 4(5) | 1(1) | 3.6(0.3–25.4) | 0.2 | |
T/T | 0(0) | 0(0) | – | – | |
rs3739821 | 0.42 | ||||
T/T | Male | 12(23) | 5(10) | Reference | Reference |
T/C | 28(53) | 31(61) | 0.4(0.1–1.5) | 0.19 | |
C/C | 13(24) | 15(29) | 0.3(0.1–1.3) | 0.11 | |
T/T | Female | 16(21) | 18(23) | Reference | Reference |
T/C | 15(66) | 45(57) | 1(0.4–2.6) | 0.83 | |
C/C | 10(13) | 16(20) | 0.7(0.2–2.4) | 0.66 | |
rs7494379 | 0.001 | ||||
C/C | Male | 16(31) | 32(63) | Reference | Reference |
C/T | 22(41) | 14(27) | 2.6(0.9–7.4) | 0.063 | |
T/T | 15(75) | 5(10) | 8.4(2.2–32.1) | 0.002 | |
C/C | Female | 32(42) | 48(61) | Reference | Reference |
C/T | 28(36) | 23(29) | 1.6(0.7–3.5) | 0.2 | |
T/T | 17(22) | 7(10) | 3(1–8.8) | 0.04 |