PubMed	EMBASE (Ovid)	CINAHL (EBSCO)
#1 "IMMUNOTHERAPY" [MeSH] OR "DESENSITIZATION, IMMUNOLOGIC" [MeSH] #2 ("Allergens/administration and dosage"[Mesh] OR "Allergens/immunology"[Mesh]) #3 ALLERGEN* [tiab] OR IMMUNOLOGIC [tiab]) AND (HYPOSENSITIZ* [tiab] OR HYPOSENSITIS* [tiab] OR DESENSITIZ* [tiab] OR DESENSITIS* [tiab]) #4 #1 OR #2 OR #3 #5 "ADMINISTRATION, SUBLINGUAL" [Mesh] #6 (SUBLINGUAL* [tiab] OR ORAL* [tiab] OR TONGUE [tiab] OR MUCOSA [tiab]) #7 #5 OR #6 #8 #4 AND #7 #9 (SLIT [tiab] OR (SUBLINGUAL* [tiab] AND IMMUNOTHERAP* [tiab])) #10 #8 OR #9 #11 (((("rhinitis, allergic, perennial"[Mesh]) OR ("rhinitis, allergic, seasonal"[Mesh]) OR ((("rhinitis"[Mesh]) OR (rhinit*[tiab])) AND (allerg*[tiab] OR "hypersensitivity"[Mesh])) OR (((("rhinitis"[Mesh]) OR (rhinit*[tiab])) OR (allerg*[tiab] OR "hypersensitivity"[Mesh])) AND ((perennial[ti] OR persistent[ti] OR nonseaosnal[ti] OR nose[ti] OR nasal[ti] OR cat*[ti] OR fur[ti] OR hair*[ti] OR dander[ti] OR dust*[ti] OR mite*[ti] OR pet*[ti] OR dog*[ti] OR cockroach*[ti]) OR (seasonal[ti] OR intermittent[ti] AND spring[ti] OR summer[ti] OR pollen[ti] OR grass*[ti] OR birch[ti] OR ragweed[ti] OR tree*[ti] OR weed*[ti] OR mugwort[ti] OR willow[ti] OR alder[ti]))) OR (hayfever[tiab] OR "hay fever"[tiab] OR pollenosis[tiab] OR pollinosis[tiab] OR SAR [tiab] OR PAR [tiab])) #12 #10 AND #11	1 IMMUNOTHERAPY/ or IMMUNOLOGICAL TOLERANCE/ or exp IMMUNOMODULATING AGENT/ or exp IMMUNOSUPPRESSIVE TREATMENT/ 2 ((ALLERGEN* or IMMUNOLOGIC) and (HYPOSENSITIZ* or HYPOSENSITIS* or DESENSITIZ* or DESENSITIS*)).tw. 3 1 or 2 4 (SUBLINGUAL* or ORAL* or TONGUE or MUCOSA).tw. 5 4 and 3 6 (SLIT or (SUBLINGUAL* and IMMUNOTHERAP*)).tw. 7 6 or 5 8 exp Allergic Rhinitis/ 9 Rhinitis/ 10 Rhinit*.tw. 1110 or 9 12 exp Hypersensitivity/ 13 allerg*.tw. 14 13 or 12 15 11 and 14 16 (perennial or persistent or nonseasonal or nose or nasal or cat* or fur or hair* or dander or dust* or mite* or pet* or dog* or cockroach*).ti. 17 (seasonal or intermittent or spring or summer or pollen or grass* or birch or ragweed or tree* or weed* or mugwort or willow or alder).ti. 18 17 or 16 19 11 or 14 20 18 and 19 21 (hayfever or "hay fever" or pollenosis or pollinosis or SAR).tw. 22 15 or 8 or 20 or 21 23 22 and 7	S1 (MH "Rhinitis, Allergic, Perennial") or (MH "Rhinitis, Allergic, Seasonal") S2 (MH "Rhinitis") S3 TX rhinit* S4 S2 or S3 S5 TX allerg* S6 (MH "Hypersensitivity") S7 S5 or S6 S8 S4 and S7 S9 TI perennial or persistent or nonseasonal or nose or nasal or cat* or fur or hair* or dander or dust* or mite* or pet* or dog* or cockroach* S10 TI seasonal or intermittent or spring or summer or pollen or grass* or birch or ragweed or tree* or weed* or mugwort or willow or alder S11 S9 or S10 S12 S5 OR S6 S13 S11 and S12 S14 TX hayfever OR "hay fever" OR pollenosis OR pollinosis OR SAR S15 S1 or S8 or S13 or S14 S16 (MH "Immunotherapy") S17 (MH "Desensitization, Immunologic") S18 TX ( ALLERGEN* OR IMMUNOLOGIC* ) and TX ( HYPOSENSITIZ* OR HYPOSENSITIS* OR DESENSITIZ* OR DESENSITIS* ) S19 S16 or S17 or S18 S20 (MH "Administration, Sublingual") S21 TX SUBLINGUAL* OR ORAL* OR TONGUE OR MUCOSA S22 S20 or S21 S23 S19 and S22 s24 TX SLIT OR TX (sublingual AND immunotherap*) S25 S23 OR S24 S26 S15 AND S25
Web of Science	BIOSIS Previews/CAB Abstracts (Ovid)	mRCT
#1 TS=rhiniti* #2 TS=(allerg* OR hypersensitivty) #3 #2 AND #1 #4 TI=(perennial or persistent or nonseasonal or nose or nasal or cat* or fur or hair* or dander or dust* or mite* or pet* or dog* or cockroach*) #5 TI=(seasonal or intermittent or spring or summer or pollen or grass* or birch or ragweed or tree* or weed* or mugwort or willow or alder) #6 #5 OR #4 #7 #6 AND #2 #8 TS=(hayfever OR "hay fever" OR pollenosis OR pollinosis OR SAR OR PAR) #9 #3 OR #7 OR #8 #10 TS=((ALLERGEN* OR IMMUNOLOGIC*) AND (HYPOSENSITIZ* OR HYPOSENSITIS* OR DESENSITIZ* OR DESENSITIS* )) #11 TS=(immunotherap*) #12 #10 OR #11 #13 TS=(SUBLINGUAL* or ORAL* or TONGUE or MUCOSA) #14 #12 AND #13 #15 SLIT #16 #14 OR #15 #17 #9 AND #16	1 IMMUNOTHERAPY/ or IMMUNOLOGICAL TOLERANCE/ or exp IMMUNOMODULATING AGENT/ or exp IMMUNOSUPPRESSIVE TREATMENT/77 2 ((ALLERGEN* or IMMUNOLOGIC) and (HYPOSENSITIZ* or HYPOSENSITIS* or DESENSITIZ* or DESENSITIS*)).tw. 3 1 or 2 4 (SUBLINGUAL* or ORAL* or TONGUE or MUCOSA).tw. 5 4 and 3 6 (SLIT or (SUBLINGUAL* and IMMUNOTHERAP*)).tw. 7 6 or 5 8 Rhinitis/ 9 Rhinit*.tw. 10 9 or 10 11 exp Hypersensitivity/ 12 allerg*.tw. 13 11 or 12 14 10 and 13 15 (perennial or persistent or nonseasonal or nose or nasal or cat* or fur or hair* or dander or dust* or mite* or pet* or dog* or cockroach*).ti. 16 (seasonal or intermittent or spring or summer or pollen or grass* or birch or ragweed or tree* or weed* or mugwort or willow or alder).ti. 17 15 or 16 18 13 AND 17 19 (hayfever or "hay fever" or pollenosis or pollinosis or SAR).tw. 20 10 or 18 OR 19 21 7 AND 20	(rhinit% OR hayfever OR allerg%) AND (sublingual% OR oral% OR tongue OR mucosa)