Table 2.
Total and differential inflammatory cell counts in bronchoalveolar lavage (BAL) fluid.
| Non-CF control (n = 24) | RSISP-CF (n = 9) | CC-CF (n = 29) | |
|---|---|---|---|
| Absolute cells x103 (/ml) | 270 (235) | 386 (453.8) | 976.5 (2516.3)** |
| Macrophages (%) | 87 (20) | 82.5 (16.1) | 49.7 (60)***^ |
| Macrophages x103 (/ml) | 158.4 (145.7) | 428.6 (337.4) | 191.1 (387.7) |
| Neutrophils (%) | 1 (5.7) | 11.2 (23.7) | 44.7 (56.4)**^ |
| Neutrophils x103 (/ml) | 3.3 (29.8) | 57.7 (101.1) | 528 (1755.1)***^ |
| Eosinophils (%) | 0.3 (0.3) | 0.3 (0.7) | 0.9 (4)* |
| Eosinophils x103 (/ml) | 0.2 (1) | 1.9 (3.1) | 17.9 (31.2)** |
| Lymphocytes (%) | 3.3 (8.7) | 6 (7.2) | 1.7 (5.3) |
| Lymphocytes x103 (/ml) | 7.3 (17.5) | 33 (43.4) | 30.8 (49.6) |
Data presented as median value (IQR) unless otherwise stated.
Statistical significance between groups was tested using a Kruskal-Wallis test followed by a Dunns post-test. * = between non-CF controls vs CC children (* ≤0.05; ** ≤0.01; *** ≤0.001); ^ = between RSISP vs CC children (^ ≤0.05).