Table 1. Effects of kratom use at low and high doses [12].

Effects of kratom at low doses (equivalent of 1-5 g of the raw leaves)	Effects of kratom at moderate to high doses (equivalent of 5-15 g of the raw leaves)
Increased work capacity, euphoria, alertness, sociability, heightened sexual desire, pupils are normal or very slightly contracted, blushing motor excitement, giddiness, loss of motor coordination (positive Romberg’s test), tremors of the extremities and face, anxiety, internal agitation (akin to akathisia) leading to dysphoria, aggressiveness, irritability	Analgesia, sedation, sweating, dizziness, nausea, dysphoria, euphoria, dreamlike state, miosis, constipation, itching