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. 2020 Feb 1;31(3):143–148. doi: 10.1091/mbc.E19-04-0207

TABLE 1:

Characteristic properties and examples of structures generated by self-assembly versus self-organization.

Involves multiple, interacting components? Displays increase in order in space/time? Requires energy input for maintenance? Distance from thermodynamic equilibrium Example of structure or system
Self-assembly Yes Yes No Near Liposome, ribosome, proteasome, bacteriophage
Self-organization Yes Yes Yes Far Mitotic spindle, actin cytoskeleton, cell cycle

Note how the structures ensuing from self-organized systems tend to display higher rates of flux, or turnover of components, than structures derived via self-assembly.