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. 2019 Dec 12;21(2):e48597. doi: 10.15252/embr.201948597

Figure 6. LSD1R838me2a/CARM1/LSD1 level is associated with grade of breast carcinoma.

Figure 6

  • A
    Typical pictures of the immunohistochemical staining of LSD1 R838me2a, LSD1, and CARM1 in breast cancer samples. Scale bars, 100 μm.
  • B–D
    The percentage of samples with high level of LSD1 R838me2a (B), LSD1 (C), and CARM1 (D) expression in different TNM stages of breast cancer (n = 70 breast tumor samples; B, P = 0.0095; C, P = 0.002; D, P = 0.0024; χ2 test).
  • E–G
    The correlation of LSD1 R838me2a with LSD1 (E), CARM1 with LSD1 R838me2a (F), and CARM1 with LSD1 (G) was statistically significant among breast cancer specimens (n = 70 breast tumor samples; E, R 2 = 0.8835, P < 0.0001; F, R 2 = 0.889, P < 0.0001; G, R 2 = 0.8478, P < 0.0001; Pearson correlation test). Note that some samples have overlapping scores. IHC score was evaluated according to Feng et al 19.

Source data are available online for this figure.