Table 2.

Multivariable logistic regression with backward selection of factors associated with the development of ACLF during hospital stay.

Parameter	OR (95% CI)	p value
MELD score (1-point increase)	1.19 (1.12–1.27)	≪0.001
Hemoglobin (1 g/dl increase)	0.81 (0.68–0.97)	0.022
Leukocyte (109/L increase)	1.11 (1.03–1.19)	0.008

Data are presented as odds ratio and 95% CI. Variables entered in the first step also included ascites, serum albumin, C-reactive protein and heart rate at hospital admission. The disease severity score to be included in the analysis was selected by the receiver-operating characteristic analysis.

ACLF, acute-on-chronic liver failure; MELD, model for end-stage liver disease.