Fig. 5.

SPECT-CT axial, coronal and sagittal imaging of GMP-Tregs at 24 h after infusion and cell distribution.

(A) Fused images showing CT (black and white) with functional colours overlay of SPEC-CT data. Top-bottom axial, coronal and sagittal. Moderate to intense uptake of indium labelled GMP-Tregs is shown in the liver and the spleen. (B) Anatomical delineation of brain, heart, lungs, liver, gut and spleen on multi-planar CT. (C) Relative uptake of indium labelled GMP-Tregs in different organs expressed as the percentage of injected activity. GMP, Good Manufacturing Practice; Treg, regulatory T cell.