Fig. 4.

Spleen stiffness or spleen length to liver stiffness ratios for HCV and ALD as a function of fibrosis stage. (A) SS to LS ratio and (B) SL to LS ratio according to fibrosis stage. Fibrosis stage was non-invasively assessed by TE using established AST-adapted cut-off values¹³ (see methods section). SS, SL to LS-ratios are always significantly higher in HCV in each fibrosis stage. Given are mean and standard deviations (unpaired test, **p≪0.01, ***p≪0.001).

ALD, alcohol-related liver disease; AST, aspartate aminotransferase; HCV, hepatitis C virus; LS, liver stiffness; SL, spleen length; SS, spleen stiffness; TE, transient elastography.