Table 3:
Cumulative incidence and proportions of late recurrences of colon and rectal cancer patients
| Category | Five-year cumulative incidence of colon cancer recurrence (95% CI) | Ten-year cumulative incidence of colon cancer recurrence (95% CI) | Proportion of late colon cancer recur-rences* | Five-year cumulative incidence of rectal cancer recurrence (95% CI) | Ten-year cumulative incidence of rectal cancer recurrence (95% CI) | Proportion of late rectal cancer recur-rences* |
|---|---|---|---|---|---|---|
| Sex | ||||||
| Females | 23% (22%−24%) | 27% (25%−28%) | 6.0% | 25% (23%−26%) | 29% (27%−31%) | 7.2% |
| Males | 26% (25%−27%) | 30% (28%−31%) | 5.5% | 27% (26%−28%) | 32% (30%−33%) | 6.9% |
| Age group at surgery date | ||||||
| <55 years | 30% (28%−33%) | 35% (32%−38%) | 5.1% | 34% (31%−37%) | 40% (36%−44%) | 6.3% |
| 55–64 years | 28% (26%−30%) | 34% (32%−36%) | 8.0% | 28% (26%−31%) | 34% (31%−37%) | 7.8% |
| 65–74 years | 25% (24%−27%) | 29% (28%−31%) | 5.4% | 26% (24%−28%) | 30% (28%−33%) | 6.8% |
| 75–84 years | 21% (20%−22%) | 24% (22%−26%) | 5.2% | 21% (19%−23%) | 24% (22%−27%) | 6.8% |
| ≥85 years | 16% (14%−18%) | 16% (14%−19%) | 1.8% | 15% (11%−20%) | 18% (13%−23%) | 6.7% |
| AJCC tumor stage | ||||||
| I | 12% (10%−14%) | 17% (14%−21%) | 10% | 13% (12%−15%) | 16% (13%−18%) | 5.8% |
| II | 18% (17%−19%) | 22% (21%−24%) | 8.4% | 20% (19%−22%) | 26% (24%−28%) | 12% |
| III | 36% (35%−38%) | 40% (38%−41%) | 3.4% | 41% (39%−43%) | 45% (43%−47%) | 4.2% |
| Lymph nodes with metastasis | ||||||
| None | 17% (16%−18%) | 21% (20%−22%) | 8.7% | 18% (17%−19%) | 23% (21%−24%) | 10% |
| 1–3 | 30% (29%−32%) | 34% (32%−36%) | 4.4% | 35% (33%−38%) | 39% (37%−42%) | 5.5% |
| 4–6 | 42% (39%−46%) | 45% (42%−49%) | 2.4% | 47% (42%−52%) | 52% (46%−57%) | 4.0% |
| 7+ | 50% (47%−54%) | 54% (50%−58%) | 2.3% | 54% (49%−59%) | 57% (51%−61%) | 1.6% |
| Calendar period for date of cancer diagnosis | ||||||
| 2001–2004 | 25% (24%−26%) | 29% (28%−30%) | 11% | 28% (26%−29%) | 32% (30%−34%) | 13% |
| 2005–2008 | 25% (24%−26%) | — † | — † | 26% (24%−27%) | — † | — † |
| 2009–2011 | — † | — † | — † | — † | — † | — † |
| Surgical technique | ||||||
| Laparotomy | 26% (25%−26%) | 29% (28%−30%) | 6.7% | 27% (25%−28%) | 31% (30%−32%) | 8.1% |
| Laparoscopy | 20% (19%−22%) | 22% (20%−24%) | 1.5% | 23% (20%−26%) | — † | — † |
| Endoscopy | 11% (3.9%−22%) | 15% (5.7%−28%) | 17% | 31% (21%−43%) | — † | — † |
| Surgical urgency | ||||||
| Elective | 22% (21%−23%) | 26% (25%−27%) | 6.5% | 26% (25%−27%) | 30% (29%−32%) | 7.1% |
| Acute | 39% (36%−41%) | 41% (38%−43%) | 3.0% | 42% (31%−53%) | — † | — † |
*
Number of late recurrences divided by total number of recurrences
†
No data reported; follow-up time is too short