Table 2.
Test substances | Dose (mg/kg/day) | Pretreatment body weight | Posttreatment body weight | Percentage change % |
---|---|---|---|---|
Distilled water | 0.2 ml | 27.1 ± 1.17 | 23.0 ± 1.08 | −1.3 |
| ||||
Methanol extract | 100 mg | 26.2 ± 0.67 | 24.2 ± 0.70 | −0.4a∗ |
200 mg | 26.9 ± 0.53 | 26.9 ± 0.58 | +0.2a∗c∗ | |
400 mg | 26.9 ± 1.00 | 27.1 ± 1.09 | +0.6a∗c∗ | |
| ||||
Aqueous extract | 100 mg | 29.1 ± 0.40 | 26.4 ± 0.43 | −0.6a∗ |
200 mg | 30.5 ± 0.34 | 28.2 ± 0.33 | −0.3a∗ | |
400 mg | 28.9 ± 0.62 | 26.7 ± 0.64 | −0.4a∗ | |
| ||||
Chloroquine | 25 mg | 26.9 ± 0.80 | 29.8 ± 0.80 | +2.1a∗bc∗ |
Values are presented as M ± SEM; n = 5; ∗(p < 0.001); a = compared to negative control; b = compared to 80% methanol extract; c = compared to aqueous extract.