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. 2020 Jan 22;2020:9749410. doi: 10.1155/2020/9749410

Table 3.

Rectal temperature of infected mice treated with 80% methanol and aqueous extracts of Terminalia brownii in the 4-day suppressive test.

Test substances Dose (mg/kg/day) Pretreatment rectal temperature Posttreatment rectal temperature Percentage change %
Distilled water 0.2 ml 35.9 ± 0.34 33.3 ± 0.31 −0.4

Methanol extract 100 mg 35.8 ± 0.28 35.8 ± 0.22 +0.1ac∗∗d
200 mg 36.5 ± 0.26 36.5 ± 0.23 +0.3ac∗∗d
400 mg 37.0 ± 0.21 37.5 ± 0.32 +0.5ac∗∗d

Aqueous extract 100 mg 36.4 ± 0.24 33.3 ± 0.25 −0.5
200 mg 36.9 ± 0.20 34.3 ± 0.19 −0.3
400 mg 35.9 ± 0.17 33.4 ± 0.18 −0.4

Chloroquine 25 mg 36.2 ± 0.15 36.7 ± 0.12 +0.7abc

Values are presented as M ± SEM; n = 5. ∗∗(p < 0.01); (p < 0.001); a = compared to negative control; b = compared to 80% methanol extract; c = compared to aqueous extract; d = compared to chloroquine.