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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Mol Psychiatry. 2019 May 28;26(3):864–874. doi: 10.1038/s41380-019-0433-1

Figure 2. Voxelwise [11C]PBR28 signal is associated with depressive symptoms and elevated in patients with mild-to-moderate depression.

Figure 2.

A. Results from the voxelwise analysis showing clusters where [11C]PBR28 SUVR is significantly positively associated with BDI. B. For visualization purposes, average SUVR from the aMCC and pgACC clusters in panel A are plotted against BDI, both adjusted for TSPO polymorphism. C. Results from the ANCOVA analysis comparing average aMCC and pgACC SUVR between cLBP patients with little-to-no depression, mild-to-moderate depression, and controls. P-values represent results from post-hoc Dunnett’s tests comparing both patient subgroups against to controls. All values have been adjusted for age, injected dose, and TSPO polymorphism.