Table 2.
Association of poor pregnancy outcome (preterm birth or preeclampsia) with gene expression in the 2nd trimester.
| Unadjusted Model | Adjusted Modela | |||||||
|---|---|---|---|---|---|---|---|---|
| Gene | Model Estimate | SE | Unadjusted p-value | FDR Adjusted p-value | Model Estimate | SE | Unadjusted p-value | FDR Adjusted p-value |
| MMD | 1.2660 | 0.5002 | 0.0215 | 0.6459 | 1.5162 | 0.5297 | 0.0113 | 0.3387 |
| PBX1 | 1.6091 | 0.7666 | 0.0511 | 0.7660 | 1.3846 | 0.8304 | 0.1149 | 0.9940 |
| TPM1 | 0.6766 | 0.4713 | 0.1693 | 0.9399 | 0.6683 | 0.5164 | 0.2140 | 0.9940 |
| ENDOD1 | 0.8428 | 0.6001 | 0.1782 | 0.9399 | 0.9984 | 0.6517 | 0.1450 | 0.9940 |
| SELP | 0.8707 | 0.7199 | 0.2430 | 0.9399 | 0.8813 | 0.7887 | 0.2803 | 0.9940 |
| GP1BB | 0.5471 | 0.5313 | 0.3176 | 0.9399 | 0.4198 | 0.5777 | 0.4780 | 0.9940 |
| PPBP | 0.7423 | 0.7508 | 0.3367 | 0.9399 | 0.5583 | 0.8161 | 0.5037 | 0.9940 |
| CMTM5 | 0.5319 | 0.5526 | 0.3493 | 0.9399 | 0.3631 | 0.5980 | 0.5522 | 0.9940 |
| PRKAR2B | 0.4874 | 0.5109 | 0.3535 | 0.9399 | 0.4536 | 0.5594 | 0.4294 | 0.9940 |
| ITGA2B | 0.5324 | 0.6139 | 0.3979 | 0.9399 | 0.4744 | 0.6718 | 0.4902 | 0.9940 |
| TREML1 | 0.4959 | 0.5811 | 0.4053 | 0.9399 | 0.3232 | 0.6292 | 0.6145 | 0.9940 |
| PROS1 | 0.5759 | 0.6865 | 0.4132 | 0.9399 | 0.5232 | 0.7516 | 0.4963 | 0.9940 |
| SDPR | 0.4066 | 0.4952 | 0.4229 | 0.9399 | 0.6214 | 0.5289 | 0.2572 | 0.9940 |
| PDE5A | 0.5378 | 0.7136 | 0.4614 | 0.9399 | 0.4709 | 0.7809 | 0.5549 | 0.9940 |
| CALD1 | 0.5269 | 0.7871 | 0.5122 | 0.9399 | 0.2899 | 0.8520 | 0.7381 | 0.9940 |
| JAM3 | 0.2158 | 0.4134 | 0.6084 | 0.9399 | 0.1708 | 0.4522 | 0.7106 | 0.9940 |
| TUBB1 | 0.2893 | 0.5727 | 0.6199 | 0.9399 | 0.1979 | 0.6253 | 0.7558 | 0.9940 |
| FSTL1 | 0.2979 | 0.5935 | 0.6221 | 0.9399 | 0.3246 | 0.6501 | 0.6244 | 0.9940 |
| FRMD3 | 0.1547 | 0.3484 | 0.6625 | 0.9399 | 0.3763 | 0.3609 | 0.3125 | 0.9940 |
| MYL9 | 0.2606 | 0.5965 | 0.6677 | 0.9399 | −0.0202 | 0.6342 | 0.9750 | 0.9940 |
| MYLK | 0.1913 | 0.4396 | 0.6689 | 0.9399 | 0.0967 | 0.4786 | 0.8424 | 0.9940 |
| SPARC | 0.1764 | 0.5739 | 0.7622 | 0.9399 | 0.0203 | 0.6226 | 0.9744 | 0.9940 |
| GUCY1B3 | −0.1426 | 0.5060 | 0.7814 | 0.9399 | −0.1950 | 0.5536 | 0.7292 | 0.9940 |
| ITGB3 | 0.1691 | 0.7431 | 0.8227 | 0.9399 | −0.0212 | 0.8071 | 0.9793 | 0.9940 |
| PF4 | 0.1243 | 0.6906 | 0.8592 | 0.9399 | 0.0632 | 0.7558 | 0.9344 | 0.9940 |
| SLC24A3 | 0.0848 | 0.4830 | 0.8626 | 0.9399 | 0.0070 | 0.5273 | 0.9895 | 0.9940 |
| ALOX12 | 0.0794 | 0.5103 | 0.8782 | 0.9399 | −0.0868 | 0.5512 | 0.8768 | 0.9940 |
| CLU | 0.0843 | 0.5631 | 0.8828 | 0.9399 | −0.0354 | 0.6133 | 0.9548 | 0.9940 |
| THBS1 | −0.0800 | 0.8299 | 0.9244 | 0.9399 | 0.0855 | 0.9045 | 0.9259 | 0.9940 |
| TTC7B | 0.0373 | 0.4872 | 0.9399 | 0.9399 | 0.0041 | 0.5335 | 0.9940 | 0.9940 |
adjusted for platelet count