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. 2020 Feb 5;15(2):e0228474. doi: 10.1371/journal.pone.0228474

Table 2. Mean differences between the groups for the different response variables measured at the discharge.

Difference Crude estimate p-value Adjusted estimate p-value
GOS at discharge
CMD Non-DOC -0.22 (-0.63;0.18) .27 -0.27 (-0.62;0.08) .132
DOC Non-DOC -1.06 (-1.57;-0.54) < .001 -1.06 (-1.59;-0.53) < .001
DOC CMD -0.83 (-1.21;-0.45) < .001 -0.79 (-1.19;-0.39) < .001
ERBI at discharge
CMD Non-DOC -35.66 (-89.44;18.12) .192 -16.19 (-69.32;36.95) .548
DOC Non-DOC -239.1 (-307.78;-170.43) < .001 -220.82 (-294.66;-146.97) < .001
DOC CMD -203.44 (-254.73;-152.16) < .001 -204.63 (-256.46;-152.8) < .001
DRS at discharge
CMD Non-DOC 3.98 (0.78;7.17) .015 1.02 (-2.27;4.3) .543
DOC Non-DOC 16.08 (12;20.16) < .001 11.89 (7.2;16.58) < .001
DOC CMD 12.1 (9.05;15.14) < .001 10.88 (7.78;13.97) < .001
LCF at discharge
CMD Non-DOC -1.06 (-1.97;-0.15) .023 -0.28 (-1.17;0.62) .544
DOC Non-DOC -4.54 (-5.7;-3.38) < .001 -3.41 (-4.72;-2.1) < .001
DOC CMD -3.48 (-4.35;-2.61) < .001 -3.13 (-4;-2.26) < .001
FAC at discharge
CMD Non-DOC -0.35 (-1.02;0.31) .298 -0.57 (-1.15;0) .051
DOC Non-DOC -1.59 (-2.44;-0.74) < .001 -2.33 (-3.11;-1.56) < .001
DOC CMD -1.24 (-1.88;-0.61) < .001 -1.76 (-2.33;-1.19) < .001
mRS at discharge
CMD Non-DOC 0.24 (-0.26;0.74) .341 0.24 (-0.19;0.67) .276
DOC Non-DOC 1.31 (0.67;1.95) < .001 1.61 (1.02;2.21) < .001
DOC CMD 1.07 (0.59;1.55) < .001 1.38 (0.96;1.79) < .001

The adjusted differences are computed using linear regression. The adjustment variables are the values at admission (excepted for FAC), the age, sex and traumatic status (TBI or non-TBI). Crude estimates of the differences (i.e. without any adjustment) are given for comparison. All differences are given with 95% confidence intervals. CMD = cognitive motor dissociation; DOC = disorders of consciousness; GOS = Glasgow Outcome Scale; ERBI = Early Barthel Index; DRS = Disability Rating Scale; LCF = Rancho Los Amigos Levels of Cognitive Functioning; FAC = Functional Ambulation Classification Scale; mRS = Modified Rankin Scale.