Table 1.
Predominant ECM proteins in WI-38 cultures identified by MS.
| Protein | UniProt accession | sequence coverage | # validated peptides | # validated spectra |
|---|---|---|---|---|
| fibronectin | P02751 | 86% | 900 | 6606 |
| collagen VI α-3 | P12111 | 75% | 519 | 3351 |
| heparan sulfate proteoglycan | P98160 | 58% | 318 | 1473 |
| fibrillin-1 | P35555 | 62% | 308 | 1123 |
| tenascin | P24821 | 67% | 190 | 910 |
| fibrillin-2 | P35556 | 61% | 256 | 904 |
| collagen VI α-1 | P12109 | 61% | 120 | 775 |
| collagen VI α-2 | P12110 | 57% | 140 | 715 |
| latent-transforming growth factor β-binding protein 1 | Q14766 | 54% | 148 | 641 |
| transforming growth factor-beta-induced protein ig-h3 | Q15582 | 69% | 88 | 633 |