Table 3.
Acute coronary syndrome types and interventions for persons living with HIV and HIV-uninfected controls presenting with acute coronary syndrome between 2004 and 2013.
| Outcome | PLWH, n = 86 | Control, n = 263 | P value | Crude OR (95% CI)a | Adjusted ORb (95% CI) | Adjusted ORc (95% CI) |
|---|---|---|---|---|---|---|
| ACS type, n (%) | ||||||
| STEMI | 25 (29) | 31 (12) | 0.0002 | 3.07 (1.68–5.60) | 5.01 (2.17–11.57) | 5.05 (1.82–14.02) |
| NSTEMI | 50 (58) | 187 (71) | 0.03 | 0.62 (0.37–1.03) | 0.37 (0.18–0.75) | 0.33 (0.14–0.79) |
| UA | 11 (13) | 45 (17) | 0.34 | 0.57 (0.26–1.22) | 0.68 (0.24–1.93) | 0.76 (0.23–2.52) |
| Intervention, n (%)d | ||||||
| Overall | ||||||
| Medical management | 23 (27) | 81 (31) | 0.46 | Ref | Ref | Ref |
| Any revascularization | 63 (73) | 181 (69) | 1.14 (0.66–1.98) | 1.51 (0.74–3.11) | 2.90 (1.01 −8.39) | |
| PCI | 46 (73) | 161 (89) | 0.002 | Ref | Ref | Ref |
| CABG | 17 (27) | 20 (11) | 2.91 (1.40–6.02) | 1.28 (0.45–3.62) | 3.55 (0.70–18.03) | |
| Among STEMI | ||||||
| Medical management | 2 (8) | 7 (23) | 0.14 | Ref | Ref | Ref |
| Any revascularization | 23 (92) | 24 (7) | 3.30 (0.62–17.69) | 3.98 (0.26–61.47) | – | |
| PCI | 19 (83) | 24 (100) | 0.05 | Ref | Ref | Ref |
| CABG | 4 (17) | 0 (0) | – | – | – | |
| Among NSTEMI/UA | ||||||
| Medical management | 21 (34) | 74 (32) | 0.72 | Ref | Ref | Ref |
| Any revascularization | 40 (66) | 157 (68) | 0.87 (0.44–1.48) | 0.89 (0.40–2.01) | 1.65 (0.51 −5.30) | |
| PCI | 27 (68) | 137 (87) | 0.003 | Ref | Ref | Ref |
| CABG | 13 (33) | 20 (13) | 3.37 (1.49–7.66) | 2.41 (0.67–8.64) | 8.90 (1.39–56.99) | |
| Stent type among patients who underwent PCI, n (%) | ||||||
| BMS | 33 (72) | 23 (16) | <0.0001 | 13.72 (5.97–31.53) | 10.04 (2.81–35.95) | 5.94 (1.33–26.55) |
| DES | 13 (28) | 125 (84) | Ref | Ref | Ref | |
All ORs conditioned on race and sex. ACS, acute coronary syndrome; BMS, bare metal stent; CABG, coronary artery bypass graft; CI, confidence interval; DES, drug-eluting stent; NSTEMI, non-ST-segment myocardial infarction; OR, odds ratio; PCI, percutaneous coronary intervention; PLWH, persons living with HIV; STEMI, ST-segment elevation myocardial infarction; UA, unstable angina.
Conditioned on race and sex.
Adjusted for age, catheterization year, smoking, hypertension, BMI, dyslipidemia, diabetes mellitus.
Adjusted for age, catheterization year, smoking, hypertension, BMI, dyslipidemia, diabetes mellitus, and Gensini score.
One control patient was transferred to an outside facility for intervention (CABG vs. PCI) and not included in this analysis.