Table 3.
Univariate and multivariate Cox proportional-hazards models of biochemical recurrence-free survival in PCa patients PSA ≤ 10 prior to radical protatectomy.
| Variable | Univariate model | Multivariate model | |||
|---|---|---|---|---|---|
| N | Hazard Ratio (95% CI) |
P value | Hazard Ratio (95% CI) |
P value | |
| Log-transformed sCD105 † | 181 | 0.58 (0.43–0.80) | <.001 | 0.63 (0.45–0.88) | 0.007 |
| Pre-surgery PSA (ng/mL) † | 181 | 1.30 (1.15–1.46) | <.001 | 1.26 (1.10–1.44) | <.001 |
| Age at surgery (Years) † | 181 | 1.02 (0.99–1.05) | 0.246 | 0.99 (0.96–1.02) | 0.558 |
| Total Gleason | |||||
| 5–6 | 60 | 0.05 (0.02–0.13) | <.001 | 0.08 (0.03–0.22) | <.001 |
| 7 | 114 | 0.20 (0.09–0.44) | <.001 | 0.19 (0.08–0.45) | <.001 |
| 8–9 | 7 | 1 (Reference) | 1 (Reference) | ||
| Surgical margin | |||||
| Yes | 42 | 2.77 (1.77–4.33) | <.001 | 3.33 (2.06–5.37) | <.001 |
| No | 139 | 1 (Reference) | 1 (Reference) | ||
| T stage | |||||
| T2 | 142 | 0.34 (0.22–0.54) | <.001 | 0.65 (0.39–1.06) | 0.087 |
| T3 | 39 | 1 (Reference) | 1 (Reference) | ||
Cox proportional hazards models were fit modeling biochemical recurrence-free survival.
181 observations were used in the multivariable model.
†
Hazard Ratio (95% CI) was expressed as 1-unit increment.