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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: J Immunol. 2020 Jan 3;204(4):923–932. doi: 10.4049/jimmunol.1900978

Figure 2. BHLHE40 is required in T cells for a normal memory response to H. polygyrus.

Figure 2.

(A) H. polygyrus-rechallenged Cd4-Cre− Bhlhe40fl/fl and Cd4-Cre+ Bhlhe40fl/fl mice were analyzed for quantitation of H. polygyrus eggs/gram feces over time. (B) Naïve and H. polygyrus-rechallenged Cd4-Cre− Bhlhe40fl/fl and Cd4-Cre+ Bhlhe40fl/fl mice were analyzed for quantitation of intestinal granulomas. (C) Naïve and H. polygyrus-rechallenged Cd4-Cre− Bhlhe40fl/fl and Cd4-Cre+ Bhlhe40fl/fl mice were analyzed by flow cytometry for quantitation of SILP myeloid cells. (D) H. polygyrus-rechallenged LysM-Cre− Bhlhe40fl/fl and LysM-Cre+ Bhlhe40fl/fl mice were analyzed for quantitation of H. polygyrus eggs/gram feces over time. (E) Naïve and H. polygyrus-rechallenged LysM-Cre− Bhlhe40fl/fl and LysM-Cre+ Bhlhe40fl/fl mice were analyzed for quantitation of intestinal granulomas. (F) Naïve and H. polygyrus-rechallenged LysM-Cre− Bhlhe40fl/fl and LysM-Cre+ Bhlhe40fl/fl mice were analyzed by flow cytometry for quantitation of SILP myeloid cells. Data are representative of or pooled from at least 2 independent experiments. Data are mean ± s.e.m. Significance calculated with an unpaired Student’s t-test.