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Anti-KRAS T-cell receptors isolated from patients with metastatic cancer treated in the Surgery Branch at the NCI in Bethesda, MD.
|
KRAS Mutation |
Patient # | Cancer Diagnosis |
CD4/CD8 | HLA- Restriction |
Method |
|---|---|---|---|---|---|
| G12D | 4095 4238 |
Colon Colon |
CD8 CD4 |
C*08:02 (8%) Class II (DR) |
TMG IVS |
| G12V | 4148 | Endometrial | CD4 CD8 |
DRB1*07:01 (25%) A*11:01 (14%) |
TMG IVS |
| G12C | 4173 | Ovarian | CD4 | DRB1*11:01 (10%) | IVS |
| G12R | 4268 | Colon | CD4 | Class II | TMG |
