Skip to main content
. 2020 Jan 30;10:3062. doi: 10.3389/fimmu.2019.03062

Table 5.

Blood cell count parametersa.

C F P1 CC CF FC FF P2
N 24 24 9 10 5 8
Total leukocyte count (109/L) 2.70 ± 0.18 2.44 ± 0.28 0.192 8.35 ± 1.92 6.22 ± 0.89* 6.22 ± 0.54 9.06 ± 1.86 0.105
Total erythrocyte count (109/L) 3.90 ± 0.09 3.71 ± 0.11 0.283 2.69 ± 0.46 3.85 ± 0.42 3.17 ± 0.39 3.29 ± 0.17 0.403
Hemoglobin 4.95 ± 0.10 4.55 ± 0.23 0.162 3.19 ± 0.56 4.58 ± 0.42 3.76 ± 0.42 3.89 ± 0.22 0.354
Hematocrit 0.28 ± 0.01 0.27 ± 0.01 0.490 0.19 ± 0.03 0.26 ± 0.02 0.22 ± 0.03 0.23 ± 0.01 0.351
MCV 72.6 ± 0.7 73.4 ± 0.8 0.583 69.4 ± 1.0 69.4 ± 0.84 70.0 ± 1.0 69.5 ± 0.8 0.993
MCHC 17.5 ± 0.1 16.7 ± 0.7 0.279 16.3 ± 0.8 17.3 ± 0.1 16.8 ± 0.4 17.0 ± 0.1 0.661
Platelets 101 ± 21 86 ± 18 0.685 464 ± 96 496 ± 53 557 ± 97 426 ± 56 0.497
MPV 13.7 ± 0.9 15.1 ± 0.7 0.280 12.3 ± 1.1 12.3 ± 0.8 15.3 ± 2.8 14.7 ± 1.3 0.980
MPC 236 ± 2 236 ± 2 0.928 242 ± 6 245 ± 4 236 ± 8 244 ± 6 0.155
Neutrophil count (109/L) 1.43 ± 0.13 1.17 ± 0.23 < 0.05 5.97 ± 1.65 3.89 ± 0.79* 3.97 ± 0.48 6.86 ± 1.83 < 0.05
Neutrophil proportion (%) 52.3 ± 2.1 43.8 ± 2.8 < 0.01 65.1 ± 4.0 57.7 ± 5.2* 64.0 ± 5.7 69.9 ± 4.8 < 0.05
Lymphocyte count (109/L) 1.08 ± 0.07 1.06 ± 0.07 0.943 1.88 ± 0.23 1.93 ± 0.16 2.01 ± 0.38 1.76 ± 0.20 0.899
Lymphocyte proportion (%) 41.3 ± 2.0 47.8 ± 2.7 < 0.05 28.7 ± 3.7 35.4 ± 4.8* 32.0 ± 5.5 25.2 ± 4.5 0.065
Monocyte count (109/L) 0.12 ± 0.02 0.12 ± 0.02 0.830 0.29 ± 0.09 0.27 ± 0.04 0.14 ± 0.02 0.20 ± 0.04 0.729
Monocyte proportion (%) 4.3 ± 0.5 4.9 ± 0.5 0.228 3.3 ± 0.4 4.5 ± 0.5* 2.2 ± 0.5 2.5 ± 0.6 < 0.05
Eosinophil count (108/L) 0.11 ± 0.02 0.09 ± 0.02 0.249 0.36 ± 0.11 0.32 ± 0.04 0.42 ± 0.10 0.95 ± 0.50 0.262
Eosinophil proportion (%) 0.4 ± 0.1 0.4 ± 0.1 0.718 0.4 ± 0.1b 0.6 ± 0.1 0.7 ± 0.2 0.9 ± 0.3 0.106
Basophil count (108/L) 0.04 ± 0.01 0.05 ± 0.01 0.717 0.08 ± 0.03 0.09 ± 0.01 0.14 ± 0.06 0.11 ± 0.04 0.975
Basophil proportion (%) 0.2 ± 0.02 0.2 ± 0.03 0.546 0.2 ± 0.05 0.2 ± 0.02 0.2 ± 0.08 0.2 ± 0.04 0.769
LUC count (108/L) 0.45 ± 0.09 0.72 ± 0.15 0.066 1.56 ± 0.38 0.94 ± 0.15 0.54 ± 0.14 1.29 ± 0.41 0.421
LUC proportion (%) 1.5 ± 0.3 2.8 ± 0.3 < 0.001 2.2 ± 0.5 1.7 ± 0.3 0.9 ± 0.02 1.5 ± 0.3 0.355
a

Values are means ± SEMs; P1 indicates the P-value comparing the two groups fed colostrum or formula on day 5, i.e., C and F; P2 indicates the P-value comparing the four 9-day groups, i.e., CC, CF, FC, and FF; the post-hoc comparison between the respective three groups and the control group (FF) was performed by Dunnett's test and significance was indicated by superscript asterisks:

*

P < 0.05.

b

CC vs. FF, P = 0.063.

C, colostrum feeding; CC, colostrum feeding until day 9; CF, 4 days colostrum feeding followed by formula feeding until day 9; CSF, cerebrospinal fluid; F, formula feeding; FC, 4 days formula feeding followed by colostrum feeding until day 9; FF, formula feeding until day 9; LUC, large unstained cells; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MPC, mean platelet component; MPV, mean platelet volume.