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. 2020 Feb 5;10:1854. doi: 10.1038/s41598-020-58906-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of CIH on body weight and number of inflammatory cells in BAL fluid in a LLC mouse model. (A) Body weight (BW) of mice in the RA or CIH groups. BW was measured weekly at a regular time. (B) Comparison of BW gain in mice (ΔBW = BW 3 weeks – BW 1 week). BAL cells were isolated and total and differential cells were (C) counted or (D) expressed in percentages to analyze inflammatory cells. The results are the means ± SD. BAL: bronchoalveolar lavage; CIH: chronic intermittent hypoxia; LLC: Lewis lung carcinoma; RA: room air; SD: standard deviation.