Table 2.
Adjusted linear regression models of the associations between pre-pregnancy body mass index and total gestational weight gain with INTER-NDA score percentiles by domain at 24-month follow-up assessment in the 2015 Pelotas (Brazil) Birth Cohort, stratified by child’s sex.
| Global | Language | Cognitive | Motor | |
|---|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | |
| Total sample | ||||
| Pre-pregnancy BMI (kg/m2)a,b | 0.000 (−0.005; 0.007) | 0.000 (−0.005; 0.006) | 0.001 (−0.004; 0.007) | 0.005 (−0.001; 0.011) |
| Total gestational weight gain (kg)c,d | −0.002 (−0.007; 0.002) | −0.001 (−0.006; 0.003) | −0.001 (−0.006; 0.003) | −0.004 (−0.01; 0.000) |
| Boys | ||||
| Pre-pregnancy BMI (kg/m2)a,b | 0.002 (−0.005; 0.011) | 0.003 (−0.005; 0.011) | 0.004 (−0.003; 0.012) | 0.003 (−0.004; 0.011) |
| Total gestational weight gain (kg)c,d | −0.007 (−0.013; −0.000) | −0.007 (−0.014; −0.000) | −0.007 (−0.014; −0.000) | −0.006 (−0.013; 0.000) |
| Girls | ||||
| Pre-pregnancy BMI (kg/m2)a,b | 0.000 (−0.008; 0.010) | −0.000 (−0.009; 0.008) | 0.001 (−0.007; 0.010) | 0.006 (−0.003; 0.015) |
| Total gestational weight gain (kg)c,d | 0.001 (−0.005; 0.008) | 0.004 (−0.002; 0.011) | 0.004 (−0.002; 0.010) | −0.002 (−0.010; 0.004) |
INTER-NDA – Intergrowth-21st Neurodevelopment Assessment. BMI – body mass index. 95% CI − 95% confidence interval.
an = 3,666. bModel adjusted for maternal age, maternal schooling, family income, maternal occupation, maternal skin color, parity, smoking in pregnancy, gestational age at birth.
cn = 3,703. dSame model as for pre-pregnancy BMI plus adjustment for the number of antenatal care appointments.