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. 2020 Feb 5;11:730. doi: 10.1038/s41467-020-14351-8

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© The Author(s) 2020, corrected publication 2022

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Fig. 6 — a A 2D density plot of the fraction of subclonal SVs versus SNVs for PCAWG samples (n = 1169) (a variant under 0.7 CCF was considered subclonal). b Survival curves representing patients divided into those with a SCNR pattern, those with high subclonal SV fraction, or neither. c A circos plots for an example SCNR pattern tumour (Liver Hepatocellular carcinoma, tumour WGS aliquot 2bff30d5-be79-4686-8164-7a7d9619d3c0). The outside track represents the copy number across the genome and the inner lines indicate SVs. Blue lines represent clonal SVs and red lines represent subclonal SVs. d A CCF histogram of sample 2bff30d5-be79-4686-8164-7a7d9619d3c0’s SNVs. e A CCF histogram of 2bff30d5-be79-4686-8164-7a7d9619d3c0’s subclonal SV’s colour coded by SV category. f A CCF histogram of 2bff30d5-be79-4686-8164-7a7d9619d3c0’s clonal SVs.