Fig. 1. Telomere content is increased in ATRX/DAXX^trunc samples.

a Overview of the telomere content distribution of all analyzed tumor types. The number of samples in each tumor type is indicated. Cohorts with sample sizes <15 are not shown. b TMM-associated mutations in different tumor types. c Telomere content in samples with different TMM-associated mutations. d TERT expression in samples with different TMM-associated mutations. The center lines of the boxplots are the medians, the bounds of the boxes represent the first and third quartiles, the upper and lower whiskers extend from the hinge to the largest or smallest value, respectively, no further than 1.5 × IQR from the hinge (where IQR is the interquartile range, or distance between the first and third quartiles). ****p < 0.0001, Wilcoxon rank-sum tests.