Table 2.

Diagnostic accuracy for significant features differentiating patients with pathologic complete response (pCR) versus non-pCR patients

		p value*	ROC-AUC	Sensitivity	Specificity	PPV	NPV	Accuracy	Cutoff
Textural features	Δ Entropy	0.024	0.71	0.67	0.73	0.56	0.81	0.71	3.78
	Δ LRE	0.021	0.71	0.73	0.70	0.55	0.84	0.71	0.57
	Δ Busyness	0.020	0.72	0.67	0.80	0.63	0.83	0.76	34.38
Dynamic features	Δ MSD	0.013	0.74	0.67	0.83	0.67	0.83	0.78	27.74
	Δ WIS	< 0.001	0.73	0.60	0.87	0.69	0.81	0.78	73.62
	Δ WOS	0.012	0.86	0.87	0.80	0.68	0.92	0.82	24.42
	SIS	< 0.001	0.93	0.93	0.87	0.78	0.96	0.89	56.47

LRE Long-run emphasis, MSD Maximum signal difference, NPV Negative predictive value, PPV Positive predictive value, ROC-AUC Receiver operating characteristic area under the curve, SIS Standardised index of shape, WIS Washin, WOS Washout slope

*Kruskal-Wallis test