Fig. 2.
Genes related to TLR signaling, inflammation, and ceramide metabolism in HipFx in comparison to matched, healthy older adult control. Individual data values for genes related to toll-like receptor signaling (A), inflammatory mediators (B), and ceramide metabolism (C) in HipFx (n = 7) before (Pre; open circles) and after (Post; closed circles) 3 mo of exercise training relative to healthy older adult control levels (CON; n = 8). Data were normalized to chemokine receptor type 2 (CCR2) using the 2 –ΔΔCt method; therefore values for CON were ~1 (dotted line). Open bar represents the mean for Pre. Grey bar represents the mean for Post. *Different from CON (P ≤ 0.05).