Skeletal muscle sphingolipids. Individual data points representing total abundance of specific skeletal muscle sphingolipids in HipFx participants (n = 5) after 3 mo exercise training (fold change relative to Pre) (A) and Pre (open circles) and Post (closed circles) abundance levels compared with matched, healthy older adult controls (n = 8; fold change relative to CON) (B). Cer, ceramide; DiHydro, dihydroceramide; CerP, phosphoceramide; SM, sphingomyelin. In Fig. 3B, open bar represents the mean for Pre and grey bar represents the mean for Post. $P = 0.07 (vs. Pre). *Different from CON (P ≤ 0.05).