Table 1.
Characteristics of patients with Crohn’s disease and the healthy population (control) in the middle-age-onset group
|
Non-CD control |
CD patients |
P value | |
| (n = 9499756) | (n = 977) | ||
| Age, yr | 50.01 ± 6.73 | 50.00 ± 6.70 | 0.961 |
| Sex | < 0.001 | ||
| Male | 4660907 (49.06) | 570 (58.34) | |
| Smoking | < 0.001 | ||
| Non-smoker | 5945314 (62.58) | 532 (54.45) | |
| Ex-smoker | 1455702 (15.32) | 204 (20.88) | |
| Current smoker | 2098740 (22.09) | 241 (24.67) | |
| Drinking | 0.355 | ||
| 0 | 5258307 (55.35) | 559 (57.22) | |
| 0-30 g | 3599536 (37.89) | 361 (36.95) | |
| > 30 g | 641913 (6.76) | 57 (55.83) | |
| Regular exercise2 | 4974091 (52.36) | 483 (49.44) | 0.067 |
| Lowest income 20%1 | 2446619 (25.75) | 234 (23.95) | 0.197 |
| Diabetes mellitus | 898517 (9.46) | 90 (9.21) | 0.792 |
| Hypertension | 2556964 (26.92) | 258 (26.41) | 0.720 |
| Dyslipidemia | 2041629 (21.49) | 167 (17.09) | 0.001 |
| Chronic kidney disease | 430175 (4.53) | 59 (6.04) | 0.023 |
| Body mass index | 23.97 ± 3.02 | 23.40 ± 3.00 | < 0.001 |
| Waist circumference | 80.54 ± 8.65 | 80.78 ± 8.81 | 0.400 |
| Systolic blood pressure | 122.43 ± 14.88 | 120.9 ± 13.88 | 0.001 |
| Diastolic blood pressure | 76.7 ± 10.19 | 75.79 ± 9.62 | 0.006 |
| Fasting glucose1 | 98.99 ± 24.11 | 96.83 ± 21.55 | 0.005 |
Values are presented as number (%) or mean ± SD.
1
Those with income in the bottom 20% of the national population.
2
Performing high-intensity exercise for > 3 d/wk for at least 30 min or moderate-intensity exercise for > 5 d/wk for at least 20 min. CD: Crohn’s disease.