Comparison 3. Combination with potassium‐sparing diuretics versus monotherapy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
3.1 Total mortality	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.24 [0.01, 5.87]
3.2 Serious adverse events	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	0.72 [0.10, 5.04]
3.3 Cardiovascular events	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.45 [0.13, 15.71]
3.4 Cardiovascular mortality	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
3.5 Withdrawals due to adverse effects	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
3.6 Reaching blood pressure control	1	200	Risk Ratio (M‐H, Fixed, 95% CI)	1.15 [0.93, 1.42]