Figure 4.

Levels of chemerin, IL-1, TNF-α, GLUT2, and PDX1 in mice. Changes in serum levels of (A) chemerin, (B) IL-1, (C) TNF-α were detected in the PDM, high-fat diet and control groups after modeling at 42 days using ELISA. Expression levels of (D) GLUT2 or (E) PDX1 were detected at 42 days in the PDM group, high-fat diet or control group by reverse transcription-quantitative PCR. *P<0.05. GLUT2, glucose transporter 2; IL, interleukin; PDX1, pancreatic and duodenal homeobox; PDM, pancreatogenic diabetes mellitus; TNF, tumor necrosis factor.