Figure 2.

HFD alters the intestinal morphology. Mice were fed an HFD for 14-weeks, and then the small intestines and colons were removed. (A) Representative images (scale bar, 2 cm), and (B) quantified length of the small intestine. (C) Representative H&E staining images of the crypt and villi in the jejunum (scale bar, 50 µm; magnification, ×40). (D) Villus length and (E) crypt depth in the small intestine. (F) Representative images of the colon of mice in the two groups (scale bar, 2 cm), and (G) quantified colon length. (H) H&E staining images of colonic crypt (scale bar, 50 µm; magnification, ×40), and (I) quantified colonic crypt depth. Data are presented as the mean ± standard deviation. *P<0.05 vs. Con group. HFD, high-fat diet; Con, control; H&E, hematoxylin and eosin.