Table I.
Cardiac function indexes after isolated heart aerobically perfused for 20 min.
| Groups | LVDP (mmHg) | HR (bpm) | LVEDP (mmHg) | +dp/dtmax (mmHg/s) |
|---|---|---|---|---|
| N | 96.9±7.4 | 306±33 | 2.63±0.92 | 3,810±300 |
| I/R | 93.0±6.6 | 312±45 | 2.43±1.27 | 3,590±146 |
| IPO | 96.4±7.1 | 301±19 | 2.37±0.92 | 3,530±364 |
| IPO+5HD | 96.8±7.0 | 287±33 | 2.43±1.27 | 3,700±141 |
| IPO+2ME2 | 94.6±5.2 | 303±34 | 2.89±0.60 | 3,550±360 |
| DPO | 96.8±8.8 | 306±26 | 2.38±0.74 | 3,550±267 |
| DPO+5HD | 93.3±8.5 | 309±28 | 2.38±0.92 | 3,810±294 |
| DPO+2ME2 | 93.9±5.2 | 308±41 | 2.22±0.67 | 3,810±457 |
| I/R+5HD | 90.8±6.2 | 298±22 | 2.33±0.52 | 3,590±370 |
| I/R+2ME2 | 96.7±5.7 | 284±17 | 2.14±1.07 | 3,510±408 |
The results are expressed as the mean ± standard error of the mean, n=8. IPO, ischemic post-conditioning; DPO, diazoxide post-conditioning; I/R, ischemia/reperfusion; 5HD, 5-hydroxydecanoic acid; 2ME2, 2-methoxyestradiol; HIF, hypoxia inducible factor; HO-1, heme-oxygenase-1; iNOS, inducible nitric oxide; VEGF, vascular endothelial growth factor; HR, heart rate; LVEDP, left ventricular end diastolic pressure; LVDP, left ventricular developed pressure.