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. 2020 Jan 14;21(3):1233–1241. doi: 10.3892/mmr.2020.10942

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Reverse transcription-quantitative polymerase chain reaction analysis of Nrf2/HO-1 expression. (A) mRNA expression levels of Nrf2. (B) mRNA expression levels of HO-1. Nrf2/HO-1 mRNA expression was revealed to be significantly lower in the IIR group compared with the control group. Pretreatment with DEX increased the mRNA expression of Nrf2/HO-1 in the IIR + DEX (30 µg/kg) group. Data are presented as the mean ± standard error of the mean. ^##P<0.01 vs. control group; **P<0.01 vs. IIR + NS group. IIR, intestinal ischemia reperfusion; DEX, dexmedetomidine; NS, normal saline; Nrf2, nuclear factor-erythroid 2 related factor 2; HO-1, heme oxygenase 1.