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Effect of Dex on renal function and body weight. (A) Body weight, (B) RI, (C) BUN and (D) Scr. Data are presented as the mean ± SEM (n=10). **P<0.01, ***P<0.001 vs. Con; #P<0.05, ##P<0.01 vs. Dex + CP. Atip, atipamezole; BUN, blood urea nitrogen; Con, control; CP, cisplatin; Dex, dexmedetomidine; Scr, serum creatinine; RI, renal index.
