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Dex protects against proximal tubular cell apoptosis induced by CP. (A) TUNEL staining assay (magnification, ×400; scale bar, 50 µm). Green, TUNEL; blue, DAPI; red arrows, TUNEL-positive cells. (B) Quantification of TUNEL-positive cells. Data are presented as the mean ± SEM (n=10). ***P<0.001 vs. Con; #P<0.05 vs. Dex + CP. Atip, atipamezole; Con, control; CP, cisplatin; Dex, dexmedetomidine; HPF, high-power field; TUNEL, terminal deoxynucleotidyl transferase dUTP nick-end labelling.
