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. 2020 Jan 16;21(3):1471–1480. doi: 10.3892/mmr.2020.10943

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Propofol inhibits DDP resistance in ovarian cancer cells. (A) A2780 and DDP-resistant A2780/DDP cells were treated with DDP and the IC₅₀ was calculated using an MTT assay to validate the sensitivity of A2780 and A2780/DDP cells to DDP. (B) A2780 and A2780/DDP cells were incubated with DDP alone or DDP combined with propofol, and cell viability was analyzed using an MTT assay. (C) Apoptotic rate of A2780 and A2780/DDP cells treated with DDP or DDP in combination with propofol was measured using flow cytometry. Data are presented as the mean ± SD, n=3. *P<0.05 and **P<0.01. DDP, cisplatin.