Figure 3.

Knockdown of miR-374a with a miR-374a inhibitor decreases the proliferation of ovarian cancer cells. A2780 cells were transfected with mimics NC, miR-374a mimics, inhibitor NC or miR-374a inhibitor. (A) miR-374a expression levels were analyzed using reverse-transcription-quantitative PCR. (B) Cell viability was assessed using the Cell Counting kit-8 assay. (C) Cell cycle progression was examined using flow cytometry. Data are presented as the mean ± SD, n=3. *P<0.05 and **P<0.01. miR, microRNA; NC, negative control; OD, optical density.