Figure 3.
Immunohistochemistry and semi-quantitative analysis for AGE, RAGE, p-ERK, MMP3 and TIMP1. In CTRL samples (A,D,G,L) all markers tested were mildly expressed in contrast to the CRSwNP samples (B,E,H,M), which showed a significant increase of immunopositivity. Regarding TIMP1, no quantitative differences were detected between the two groups (O,P). Data were confirmed by semi-quantitative analysis (C,F,I,N,Q). Original magnification 10×, scale bar: 100 µm.