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. 2019 Nov 18;24(11):118001. doi: 10.1117/1.JBO.24.11.118001

Table 1.

LD50 of pancreatic cell lines of sodium porfimer and verteporfin-PDT. After 6 h of incubation with sodium porfimer or verteporfin followed by photoradiation at a light dose of 60  J/cm2 (PDT) for 2 min and incubation for another 96 h, comparable dead cell rates were found in pancreatic cell lines. LD50 was counted by SPSS19.0 software.

Cell lines Photosensitizer
Sodium porfimer (μg/ml)
Verteporfin (μg/ml)
LD50 95% CI LD50 95% CI
HPNE 0.44 0.32 to 0.58 0.005 0.005 to 0.006
BxPC-3 0.85 0.59 to 1.21 0.008 0.006 to 0.012
CAPAN-2 1.29 0.90 to 1.87 0.016 0.013 to 0.019
MIA PaCa-2 1.02 0.60 to 1.75 0.015 0.011 to 0.020
PANC-1 0.77 0.50 to 1.16 0.007 0.006 to 0.008