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The ROR depletion induces apoptosis of gastric cancer MDR cells. Cell apoptosis rates of SGC7901, SGC7901/ADR, SGC7901/VCR, and SGC7901/ADR + VCR cells with or without shROR expression in the presence of the ADR (1 mg/mL) or VCR (2 mg/mL) for 48 hours were determined. ADR indicates adriamycin; MDR, multidrug resistance; ROR, regulator of reprogramming; shROR, ROR short hairpin RNA; VCR, vincristine.
