TABLE A4.
Subgroup Analysis Based on QUADAS-2 Scorea
| Test | Absolute Sensitivity | Absolute Specificity | Diagnostic Odds Ratio [Rank] | Superiority Index [Rank] | Relative Sensitivity | Relative Specificity | Data Sets, n | Studies, n |
|---|---|---|---|---|---|---|---|---|
| Score = 7 | ||||||||
| Any tear | ||||||||
| MRA | 0.75 (0.42-0.95) |
0.74 (0.32-0.96) |
28.52 (0.94-160.41) [1] |
1.66 (0.20-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
4 | 4 |
| MRI | 0.81 (0.67-0.90) |
0.69 (0.48-0.86) |
12.43 (3.31-33.65) [3] |
1.39 (0.20-5.00) [3] |
1.13 (0.79-1.94) |
1.03 (0.58-2.20) |
9 | 7 |
| US | 0.80 (0.67-0.89) |
0.75 (0.56-0.89) |
15.27 (4.60-39.26) [2] |
1.74 (0.20-5.00) [2] |
1.12 (0.80-1.91) |
1.12 (0.67-2.37) |
13 | 11 |
| FT tear | ||||||||
| MRA | 0.86 (0.43-0.99) |
0.89 (0.44-1.00) |
552.22 (2.40-2043809.18) [1] |
2.38 (0.20-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
2 | 2 |
| MRI | 0.89 (0.57-0.99) |
0.81 (0.48-0.94) |
58.99 (4.23-602.78) [3] |
0.99 (0.20-3.00) [3] |
1.08 (0.64-2.08) |
0.97 (0.50-1.93) |
4 | 4 |
| US | 0.89 (0.69-0.97) |
0.91 (0.80-0.96) |
103.73 (17.94-411.22) [2] |
1.49 (0.20-5.00) [2] |
1.08 (0.78-2.06) |
1.09 (0.82-2.10) |
7 | 7 |
| PT tear | ||||||||
| MRA | 0.85 (0.48-0.99) |
0.81 (0.45-0.97) |
154.43 (2.62-933.62) [1] |
3.00 (0.20-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
3 | 3 |
| MRI | 0.69 (0.40-0.89) |
0.73 (0.38-0.94) |
11.40 (0.99-45.01) [3] |
0.86 (0.20-3.00) [3] |
0.83 (0.45-1.49) |
0.94 (0.44-1.78) |
4 | 4 |
| US | 0.69 (0.45-0.87) |
0.80 (0.53-0.95) |
15.68 (1.81-58.22) [2] |
1.23 (0.20-5.00) [2] |
0.84 (0.50-1.48) |
1.02 (0.64-1.80) |
6 | 6 |
| Score = 8 | ||||||||
| Any tear | ||||||||
| MRA | 0.87 (0.60-0.97) |
0.75 (0.32-0.96) |
67.44 (2.48-338.83) [2] |
1.64 (0.20-5.00) [2] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
4 | 3 |
| MRI | 0.90 (0.82-0.95) |
0.88 (0.75-0.95) |
91.21 (24.27-226.29) [1] |
3.36 (1.00-5.00) [1] |
1.05 (0.89-1.48) |
1.28 (0.86-2.75) |
9 | 7 |
| US | 0.82 (0.66-0.91) |
0.76 (0.61-0.87) |
18.28 (5.12-47.06) [3] |
0.45 (0.20-1.00) [3] |
0.95 (0.73-1.38) |
1.11 (0.70-2.37) |
12 | 10 |
| FT tear | ||||||||
| MRA | 0.90 (0.46-1.00) |
0.80 (0.32-1.00) |
1096.80 (1.40-18391778.49) [1] |
2.52 (0.20-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
3 | 3 |
| MRI | 0.87 (0.70-0.95) |
0.87 (0.64-0.97) |
63.03 (9.36-346.21) [2] |
1.59 (0.20-5.00) [2] |
1.02 (0.73-1.90) |
1.24 (0.72-2.78) |
6 | 6 |
| US | 0.84 (0.61-0.95) |
0.82 (0.61-0.94) |
29.44 (5.33-139.67) [3] |
0.82 (0.20-3.00) [3] |
0.98 (0.65-1.83) |
1.16 (0.69-2.64) |
7 | 7 |
| PT tear | ||||||||
| MRA | 0.81 (0.41-0.97) |
0.81 (0.33-1.00) |
55.50 (1.08-122796.87) [1] |
2.75 (0.20-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
2 | 2 |
| MRI | 0.74 (0.46-0.91) |
0.84 (0.60-0.95) |
18.97 (2.89-118.01) [2] |
1.71 (0.33-5.00) [2] |
0.97 (0.55-1.86) |
1.16 (0.66-2.55) |
4 | 4 |
| US | 0.53 (0.32-0.75) |
0.85 (0.66-0.94) |
7.16 (1.46-30.05) [3] |
0.59 (0.20-3.00) [3] |
0.70 (0.39-1.34) |
1.17 (0.72-2.55) |
7 | 7 |
| Score = 9 | ||||||||
| Any tear | ||||||||
| MRA | 0.85 (0.76-0.91) |
0.90 (0.83-0.95) |
65.18 (22.06-146.99) [1] |
3.54 (1.00-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
17 | 15 |
| MRI | 0.83 (0.77-0.88) |
0.79 (0.72-0.85) |
20.77 (10.56-36.26) [3] |
0.68 (0.20-3.00) [3] |
0.98 (0.88-1.11) |
0.88 (0.79-0.97) |
29 | 25 |
| US | 0.84 (0.78-0.89) |
0.81 (0.73-0.87) |
24.16 (11.76-43.90) [2] |
1.09 (0.20-3.00) [2] |
0.99 (0.89-1.12) |
0.89 (0.80-0.99) |
28 | 23 |
| FT tear | ||||||||
| MRA | 0.94 (0.82-0.99) |
0.93 (0.83-0.98) |
468.91 (43.76-1861.43) [1] |
4.44 (1.00-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
11 | 11 |
| MRI | 0.89 (0.79-0.95) |
0.85 (0.74-0.92) |
55.22 (16.11-135.21) [2] |
0.79 (0.20-3.00) [2] |
0.95 (0.84-1.09) |
0.91 (0.80-1.03) |
16 | 16 |
| US | 0.87 (0.78-0.92) |
0.84 (0.73-0.92) |
42.45 (13.19-102.77) [3] |
0.48 (0.20-3.00) [3] |
0.92 (0.82-1.06) |
0.91 (0.79-1.03) |
14 | 14 |
| PT tear | ||||||||
| MRA | 0.75 (0.60-0.88) |
0.90 (0.80-0.96) |
35.77 (9.49-93.90) [1] |
4.28 (1.00-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
10 | 10 |
| MRI | 0.55 (0.43-0.67) |
0.81 (0.71-0.87) |
5.64 (2.65-10.64) [3] |
0.33 (0.20-1.00) [3] |
0.74 (0.55-0.99) |
0.90 (0.78-1.02) |
18 | 18 |
| US | 0.56 (0.42-0.71) |
0.87 (0.79-0.92) |
9.73 (3.92-20.02) [2] |
1.06 (0.20-3.00) [2] |
0.75 (0.53-1.05) |
0.97 (0.87-1.09) |
15 | 15 |
| Score = 10 | ||||||||
| Any tear | ||||||||
| MRA | 0.91 (0.85-0.95) |
0.91 (0.85-0.95) |
130.24 (47.81-274.53) [1] |
3.87 (1.00-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
17 | 13 |
| MRI | 0.86 (0.79-0.90) |
0.89 (0.80-0.94) |
53.57 (20.97-108.59) [2] |
1.07 (0.20-3.00) [2] |
0.94 (0.86-1.01) |
0.97 (0.87-1.06) |
24 | 17 |
| US | 0.80 (0.66-0.90) |
0.88 (0.80-0.94) |
37.64 (11.56-90.10) [3] |
0.56 (0.20-3.00) [3] |
0.88 (0.72-1.00) |
0.97 (0.87-1.06) |
14 | 14 |
| FT tear | ||||||||
| MRA | 0.90 (0.68-0.99) |
0.93 (0.68-1.00) |
934.19 (13.30-5459.56) [1] |
3.21 (0.33-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
7 | 5 |
| MRI | 0.90 (0.81-0.95) |
0.89 (0.74-0.96) |
99.85 (20.03-291.61) [2] |
1.32 (0.20-5.00) [2] |
1.00 (0.86-1.33) |
0.97 (0.79-1.31) |
12 | 12 |
| US | 0.75 (0.49-0.92) |
0.89 (0.69-0.98) |
59.43 (4.60-263.72) [3] |
0.60 (0.20-3.00) [3] |
0.84 (0.53-1.18) |
0.97 (0.74-1.32) |
7 | 7 |
| PT tear | ||||||||
| MRA | 0.85 (0.73-0.91) |
0.89 (0.77-0.94) |
54.45 (14.58-127.76) [1] |
3.06 (0.33-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
8 | 6 |
| MRI | 0.73 (0.59-0.85) |
0.88 (0.78-0.93) |
23.44 (7.56-52.95) [2] |
1.05 (0.20-3.00) [2] |
0.87 (0.69-1.05) |
0.99 (0.86-1.15) |
7 | 7 |
| US | 0.66 (0.38-0.87) |
0.88 (0.73-0.95) |
21.32 (3.33-71.67) [3] |
0.95 (0.20-3.00) [3] |
0.78 (0.45-1.06) |
0.99 (0.82-1.16) |
6 | 6 |
| Score = 11 | ||||||||
| Any tear | ||||||||
| MRA | 0.83 (0.73-0.90) |
0.89 (0.77-0.96) |
52.94 (13.91-141.90) [1] |
3.56 (0.33-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
17 | 12 |
| MRI | 0.77 (0.63-0.87) |
0.87 (0.75-0.94) |
29.63 (7.61-78.05) [2] |
1.68 (0.33-5.00) [2] |
0.93 (0.75-1.11) |
0.98 (0.83-1.14) |
14 | 10 |
| US | 0.74 (0.54-0.88) |
0.70 (0.52-0.85) |
8.82 (1.97-25.39) [3] |
0.36 (0.20-1.00) [3] |
0.89 (0.65-1.11) |
0.79 (0.57-0.99) |
8 | 7 |
| FT tear | ||||||||
| MRA | 0.92 (0.80-0.97) |
0.91 (0.75-0.98) |
245.15 (28.59-905.13) [1] |
3.96 (1.00-5.00) [1] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
8 | 8 |
| MRI | 0.80 (0.52-0.95) |
0.83 (0.63-0.93) |
36.99 (3.95-138.87) [3] |
0.70 (0.20-3.00) [3] |
0.87 (0.56-1.07) |
0.91 (0.68-1.13) |
7 | 7 |
| US | 0.84 (0.66-0.94) |
0.84 (0.67-0.94) |
42.51 (7.75-127.78) [2] |
0.85 (0.20-3.00) [2] |
0.91 (0.73-1.07) |
0.93 (0.74-1.12) |
6 | 6 |
| PT tear | ||||||||
| MRA | 0.71 (0.55-0.82) |
0.82 (0.63-0.94) |
16.45 (3.25-51.45) [1] |
2.58 (0.33-5.00) [2] |
1.00 (1.00-1.00) |
1.00 (1.00-1.00) |
8 | 7 |
| MRI | 0.72 (0.56-0.82) |
0.82 (0.64-0.93) |
15.35 (3.34-44.48) [2] |
2.68 (0.33-5.00) [1] |
1.02 (0.78-1.34) |
1.00 (0.76-1.30) |
10 | 8 |
| US | 0.59 (0.36-0.80) |
0.67 (0.44-0.87) |
4.29 (0.76-14.45) [3] |
0.40 (0.20-1.00) [3] |
0.85 (0.49-1.22) |
0.82 (0.55-1.09) |
5 | 5 |
aData are reported as mean (95% CI) unless otherwise indicated. FT, full-thickness; MRA, magnetic resonance arthrography; MRI, magnetic resonance imaging; PT, partial-thickness; US, ultrasound.