Table 1.
Effects of Stellaria media on left ventricular morphological and functional parameters. Transthoracic echocardiographic measurement values in rats fed either cholesterol-enriched (HChol), cholesterol-enriched + Stellaria media (HChol + SM), or normal diet (Cont). Results are means ± SEM (n = 8 in each group), analyzed by one-way ANOVA with the Tukey post hoc test. 2D: two dimensional; 4CH: four chambers view; MM: M (motion) Mode; ns: not significant.
| Parameter (unit) | View/mode | Week 8 | Significance | ||
|---|---|---|---|---|---|
| Cont | HChol | HChol + SM | |||
| Anterior wall thickness-systolic (mm) | Short axis/MM | 3.57 ± 0.11 | 3.41 ± 0.17 | 3.10 ± 0.12 | ns |
| Anterior wall thickness-diastolic (mm) | Short axis/MM | 2.20 ± 0.11 | 2.22 ± 0.17 | 2.16 ± 0.11 | ns |
| Inferior wall thickness-systolic (mm) | Short axis/MM | 3.85 ± 0.11 | 3.46 ± 0.15 | 3.69 ± 0.09 | ns |
| Inferior wall thickness-diastolic (mm) | Short axis/MM | 2.14 ± 0.09 | 2.13 ± 0.14 | 2.19 ± 0.13 | ns |
|
| |||||
| Posterior wall thickness-systolic (mm) | Long axis/MM | 3.82 ± 0.08 | 3.68 ± 0.12 | 3.62 ± 0.09 | ns |
| Posterior wall thickness-diastolic (mm) | Long axis/MM | 2.19 ± 0.03 | 2.39 ± 0.13 | 2.52 ± 0.19 | ns |
| Septal wall thickness-systolic (mm) | Long axis/MM | 3.79 ± 0.06 | 3.62 ± 0.12 | 3.54 ± 0.17 | ns |
| Septal wall thickness-diastolic (mm) | Long axis/MM | 2.50 ± 0.11 | 2.24 ± 0.10 | 2.35 ± 0.11 | ns |
|
| |||||
| Left ventricular end-diastolic volume (μl) | 4CH/2D | 127 ± 15 | 129 ± 13 | 105 ± 13 | ns |
| Left ventricular end-systolic volume (μl) | 4CH/2D | 49 ± 8 | 53 ± 5 | 46 ± 6 | ns |
| Stroke volume (μl) | 4CH/2D | 79 ± 8 | 76 ± 8 | 59 ± 8 | ns |
| Ejection fraction (%) | 4CH/2D | 63 ± 2 | 59 ± 1 | 56 ± 3 | ns |
| Heart rate (1/min) | 4CH/2D | 343 ± 14 | 367 ± 8 | 370 ± 11 | ns |