Table 4.
HRs of incident ESKD associated with validated events of hospitalization with acute decompensated heart failure
| Model | Overall (529 Events) | Subtype of Heart Failure, HR (95% CI) | |
|---|---|---|---|
| HFpEF (247 Events)a | HFrEF (220 Events)a | ||
| Model 1 | 19.17 (13.56 to 27.11) | 22.57 (14.66 to 34.77) | 15.94 (9.19 to 27.65) |
| Model 2 | 9.12 (6.34 to 13.12) | 9.85 (6.17 to 15.72) | 9.81 (5.55 to 17.32) |
| Model 3 | 6.81 (4.60 to 10.08) | 7.58 (4.69 to 12.23) | 5.56 (2.99 to 10.36) |
Model 1 adjusted for age, sex, and race. Model 2 additionally adjusted for body mass index, ever smoking, ever drink, years of education, systolic BP, antihypertensive drugs, diabetes, eGFR, ACR, CRP, total cholesterol, HDL-C, and history of COPD and cancer, with covariates updated when available. Model 3 additionally adjusted for CVD subtypes (e.g., atrial fibrillation, coronary heart disease, and stroke).
a
Sixty two individuals were excluded from analysis because of a lack of information on ejection fraction.